Endocrine Abstracts

Introduction: A pituitary adenoma is directly assumed to originate from anterior pituitary. It is expected that pathologies of posterior hypophysis cause diabates insipitus (DI). However recently posterior pituitary tumors (PPTs) are also declared which are not associated with DI in contrast to what is expected. Rather they have a clinical and radiologic presentation akin to anterior pituitary adenomas. Differentiation of two conditions is mainly based on pathologic immunohyst...

Introduction: Hypophysitis is a rare pituitary inflammation due to primary and secondary causes. Xanthomatous hypophysitis is the rarest subtype and described with lipid-laden cystic areas, transparent cytoplasmic and lipid-laden histiocytes and foamy (xanthomatous) histiocytes. Although the etiology of xanthomatous hypophysitis is not clearly known, it has been suggested to develop as a result of autoimmune cause or inflammatory process of infiltration of cyst components from...

Introduction: Hypophysitis is a rare condition characterized by inflamation of the pituitary gland, causing mass effect and hypopituitarism. The incidence is estimated to be 1in9 million/year. The diagnosis of hypophysitis is based on clinical and laboratory findings, imaging methods and histopathology in selected cases. The aim of the treatment is to eliminate the compression effects of the mass and to treat hypopituitarsim. The first choice in medical treatment is immunsupre...

Introduction: Graves disease (GD) is an autoimmune disease in which thyrotropin receptor antibodies overactive the thyroid gland. Therefore, antithyroid drugs, radioactive iodine therapy, or surgical interventions are treatment options. In GD, pathology after thyroidectomy may include hypertrophy and hyperplasia in thyrocytes, mononuclear cell infiltration in the stroma, and increased blood supply. We presented a case with areas of necrosis and vasculitis due to GD in the path...

Introductıon: Rathke’s cleft cysts (RCCs) are benign lesions originating from the epithelial remnants of Rathke’s pouch with a peak incidence at 30–50 years of age. It is detected at a rate of 13–33% in several autopsy series. RCC is usually asymptomatic and diagnosed incidentally. In symptomatic cases, common symptoms are headache, visual disturbance, and symptoms related to hypopituitarism.Case: A 28-year-old male patient prese...

Background: Anxiety level is higher in the samples consisting of people diagnosed with pituitary adenoma, including patients with acromegaly, compared to the normal population. A higher level of anxiety indicates a lower Quality of Life (QoL) in acromegaly. This study aimed to evaluate and discuss the possible relationship between anxiety and NS in people with acromegaly.Method: This cross-sectional comparative study included an acromegaly group (AG, <em...

Background: Hypophysitis is a rare group of disease characterized with infla mmation of the pituitary gland. Rarity of the disease obviates development of a treatment strategy. We aimed to present the nationwide data of the demographics, clinical and radiological characteristics, treatment modalities and responses of the patients diagnosed with hypophysitis in a retrospective manner.Methods: The endocrinology clinics all over the country were invited to ...